Lipoprotein (a) used to be the forgotten lipid. Not anymore.

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Lipoprotein (a) — or its abbreviation, Lp(a), pronounced “el-pee-little-a” — is emerging from obscurity. And for good reason. Among them, Bob Harper, the TV famous trainer from The Biggest Loser, has helped bring Lp(a) to national attention after his heart attack in 2017. Put simply, Lp(a) is a version of LDL that is more dangerous. It is more pro-inflammatory and more pro-thrombotic. Studies show that elevated Lp(a) levels correlate with increased cardiac risk. So, it makes sense that we would want to lower patients’ elevated Lp(a) levels to reduce cardiac risk, right? So far, that hasn’t been very successful. Unfortunately, Lp(a) does not respond well to lifestyle changes. Its level is almost entirely genetically determined and cannot be easily manipulated with environmental exposures (nutrition and exercise) the way that LDL can. The best treatments for lowering Lp(a) are niacin and a drug class called CETP inhibitors. The problem, however, is that despite...
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Lipoprotein (a) used to be the forgotten lipid. Not anymore. was originally posted by Ketogenic Diet