The 6 common features of cancer

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To understand cancer as a whole, rather than as individual cancers, it is useful to find out those traits that are common to all cancers. One of the most widely cited papers in oncology is ‘Hallmarks of Cancer‘ which initially listed 6 hallmarks and then updated in 2011 with two more. This is a crucial step to defining cancer’s common features – these 8 hallmarks. Despite cancer’s many hundreds of different mutations, all cancers share these commonalties so, these must be critical features for survival that are being naturally selected as noted in ‘Darwin’s theory of evolution or why cancer is not simply a result of random mutations‘. So, how are all cancers are similar? First, we know that cancer cells are derived from originally normal cells. Breast cancer is derived from normal breast tissue and retains some its features, like estrogen receptors. Prostate cancer cells are derived from normal prostate cells and retain some of those features like sensitivity...
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